Hi everyone, Another way to get around the "unknown developer" problem is to right-click the package and then select "Open". For users that are using Macs with Apple Silicon, Phenix will run in translation mode. From some basic testing of phenix.refine, the performance on the M1 Macbook Pro 13" in translation mode is similar to a 2018 Mac mini (3.2 GHz Intel i7, 32 GB RAM). The Phenix GUI should work with XQuartz, Coot, and PyMOL since they would also run in translation mode. Also, running the command-line installer on M1 macs will need the "--try-unsupported" flag (you will get an error message stating as much). Let us know if you encounter issues running on the M1 macs. Thanks! -- Billy K. Poon Research Scientist, Molecular Biophysics and Integrated Bioimaging Lawrence Berkeley National Laboratory 1 Cyclotron Road, M/S 33R0345 Berkeley, CA 94720 Tel: (510) 486-5709 Fax: (510) 486-5909 Web: https://phenix-online.org On Sun, Jan 24, 2021 at 5:54 PM Aaron Oakley wrote:

FYI, if anyone using OS X finds that it refuses to run the point-and-click installer because the package is from an “unknown developer”, try running the following from a terminal:

xattr -dr com.apple.quarantine ~/Downloads/phenix-1.19.1-4122-mac-intel-osx-x86_64.pkg

Cheers,

–å

On 25 Jan 2021, at 11:44 am, Paul Adams wrote:

The Phenix developers are pleased to announce that version 1.19.1 of Phenix is now available (build 1.19.1-4122). This fixes bugs in the 1.19 release. If you have previously downloaded 1.19 we recommend upgrading to 1.19.1. Binary installers for Linux, Mac OSX, and Windows platforms, and the source installer, are available at the download site:

http://phenix-online.org/download/

Highlights for the 1.19.1 version of Phenix:

- phenix.real_space_refine - Fix bug in restoring previous jobs - Clarify NCS options

Please note that this new publication should be used to cite the use of Phenix:

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix. Liebschner D, Afonine PV, Baker ML, Bunkóczi G, Chen VB, Croll TI, Hintze B, Hung LW, Jain S, McCoy AJ, Moriarty NW, Oeffner RD, Poon BK, Prisant MG, Read RJ, Richardson JS, Richardson DC, Sammito MD, Sobolev OV, Stockwell DH, Terwilliger TC, Urzhumtsev AG, Videau LL, Williams CJ, Adams PD: Acta Cryst. (2019). D75, 861-877. https://doi.org/10.1107/S2059798319011471

Full documentation is available here:

http://www.phenix-online.org/documentation/

There is a Phenix bulletin board:

http://www.phenix-online.org/mailman/listinfo/phenixbb/

Please consult the installer README file or online documentation for installation instructions.

Direct questions and problem reports to the bulletin board or:

[email protected] and [email protected]

Commercial users interested in obtaining access to Phenix should visit the Phenix website for information about the Phenix Industrial Consortium.

The development of Phenix is principally funded by the National Institute of General Medical Sciences (NIH) under grant P01-GM063210. We also acknowledge the generous support of the members of the Phenix Industrial Consortium.

-- Paul Adams Division Director, Molecular Biophysics & Integrated Bioimaging, LBL ( http://biosciences.lbl.gov/divisions/mbib) Principal Investigator, Computational Crystallography Initiative, LBL ( http://cci.lbl.gov) Vice President for Technology, the Joint BioEnergy Institute ( http://www.jbei.org) Principal Investigator, ALS-ENABLE, Advanced Light Source ( http://als-enable.lbl.gov) Division Deputy for Biosciences, Advanced Light Source ( https://als.lbl.gov) Laboratory Research Manager, ENIGMA Science Focus Area ( http://enigma.lbl.gov) Adjunct Professor, Department of Bioengineering, U.C. Berkeley ( http://bioeng.berkeley.edu) Adjunct Professor, Comparative Biochemistry, U.C. Berkeley ( http://compbiochem.berkeley.edu)

Building 33, Room 250 Building 978, Room 4126 Building 977, Room 180C Tel: 1-510-486-4225 http://cci.lbl.gov/paul

Lawrence Berkeley Laboratory 1 Cyclotron Road BLDG 33R0345 Berkeley, CA 94720, USA.

Executive Assistant: Ashley Dawn [ [email protected] ][ 1-510-486-5455 ] --

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