Hello, Coot has a feature called "find un-modeled blobs" to do this interactively, but it won't suggest what could go in the blobs so you still have to figure it out from all things present in your buffer. I don't know if phenix has a program for this. I hope this helps, Guillaume ________________________________ From: [email protected] on behalf of Dmitry Semchonok Sent: Sunday, December 17, 2023 7:34:50 PM To: Phenix email list Subject: [phenixbb] unassigned densities Dear colleagues, Is there a way to assign cryo-EM densities not included in the model sequence? Do you have any tools that can help? More closely, is there a way to screen the cryo-EM map + model, point out the unassigned densities, and provide the possible structures to fit in (e.g., water molecules, etc.)? Thank you. Kind regards, Dmitry VARNING: Klicka inte på länkar och öppna inte bilagor om du inte känner igen avsändaren och vet att innehållet är säkert. CAUTION: Do not click on links or open attachments unless you recognise the sender and know the content is safe. När du har kontakt med oss på Uppsala universitet med e-post så innebär det att vi behandlar dina personuppgifter. För att läsa mer om hur vi gör det kan du läsa här: http://www.uu.se/om-uu/dataskydd-personuppgifter/ E-mailing Uppsala University means that we will process your personal data. For more information on how this is performed, please read here: http://www.uu.se/en/about-uu/data-protection-policy