Well they aren't conserved so I guess I'll have to do some manual
remodelling. The new version of HHPred is nice about building you a quick
homology model to start with though (using Modeller).
Thanks Tom!
On 22 March 2012 00:56, Terwilliger, Thomas C
Hi Morten,
I asked about this...and if your input model has Cys-Cys disulfides and the sequence file also has these cysteine residues, then the disulfides should be maintained by Rosetta. If that isn't happening, let me know!
I hope that helps! All the best, Tom T
------------------------------ *From:* [email protected] [ [email protected]] on behalf of Morten Groftehauge [ [email protected]] *Sent:* Wednesday, March 21, 2012 8:25 AM *To:* PHENIX user mailing list *Subject:* [phenixbb] Rosetta and disulphides
Hi phenix-bb'ers,
Is there anyway to make phenix.mr_rosetta take disulphide bridges into account? It's a rather enormous restraint on conformational space after all (wait is that a constraint or restraint? I get confused).
Cheers, Morten
-- Morten K Grøftehauge, PhD Pohl Group Durham University
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-- Morten K Grøftehauge, PhD Pohl Group Durham University