23 Mar
2011
23 Mar
'11
12:58 p.m.
On Wed, Mar 23, 2011 at 5:50 AM,
I guess the manual method of weight picking is not as objective as the Rfree minimization... That is one of the reasons I would like to know if there is any reason not to use weight optimization during refinement, whatever rmsds it might result to.
Yes: it takes much longer to run. I agree with Pavel, these statistics are excellent for 2.0A resolution - I wouldn't worry about the unusually low geometry deviations if everything else makes sense. -Nat