Dear Haiguang, I for one have been using OS X El Capitan for a good long while now with no problems… Please could you give more information as to what the exact problem is? I.e. where you are trying to install and so on. Thanks & best wishes Graeme From: [email protected] [mailto:[email protected]] On Behalf Of Haiguang Liu Sent: 20 September 2016 12:47 To: [email protected] Subject: [cctbxbb] rpath problem on Mac system Dear CCTBX developing team, Is there already a solution for the run path problem in the new Mac OS? The System Integrity Protectionhttps://support.apple.com/en-us/HT204899 does not allow relative run path. I temporarily disabled this feature to run the programs that requires boost (for example). If there is already a solution, please let me know. Thanks, Haiguang -- This e-mail and any attachments may contain confidential, copyright and or privileged material, and are for the use of the intended addressee only. If you are not the intended addressee or an authorised recipient of the addressee please notify us of receipt by returning the e-mail and do not use, copy, retain, distribute or disclose the information in or attached to the e-mail. Any opinions expressed within this e-mail are those of the individual and not necessarily of Diamond Light Source Ltd. Diamond Light Source Ltd. cannot guarantee that this e-mail or any attachments are free from viruses and we cannot accept liability for any damage which you may sustain as a result of software viruses which may be transmitted in or with the message. Diamond Light Source Limited (company no. 4375679). Registered in England and Wales with its registered office at Diamond House, Harwell Science and Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom